Department: Mechanical & Aerospace Engineering
Research Institute Affiliation: Agile - CaliBaja Center for Resilient Materials & Systems
Faculty Advisor(s): Joanna M. McKittrick | Marc A. Meyers

Primary Student
Name: Steven Eric Naleway
Email: snaleway@ucsd.edu
Phone: 858-534-5425
Grad Year: 2016

The recent interest in biocompatible and bioabsorbable bone implants over permanent devices has driven a multitude of research into bioinspired designs. Key to these designs is mimicking the complex hierarchical structure of cortical bone, which displays porosity on multiple length scales including larger osteons and smaller lacuna spaces. It is this porosity that promotes healthy bone growth. We present a novel method for the fabrication of bioinspired, hydroxyapatite-based materials that mimic this complex and hierarchical porosity. In this, smaller porosity is created by the freeze casting technique, where a ceramic scaffold is templated by the growth of ice crystals, while larger porosity is templated through the use of 3D printed structures. This results in final scaffolds with interpenetration between porosity at two length scales. The 3D printing process allows for a high level of control over the final porosity size and shape. Applications as biomedical implant materials will be discussed. This work is supported by funding provided by the Multi-University Research Initiative through the Air Force Office of Scientific Research (AFOSR-FA9550-15-1-0009).

Industry Application Area(s)
Life Sciences/Medical Devices & Instruments | Materials

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