1. a smart bandage with closed-loop integrated drug delivery

Department: Electrical & Computer Engineering
Research Institute Affiliation: Agile Center for Wearable Sensors (CWS)
Faculty Advisor(s): Drew A. Hall | Sheng Xu

Primary Student
Name: Da Ying
Email: dying@ucsd.edu
Phone: 615-609-7981
Grad Year: 2020

Student Collaborators
Zhenlong Huang, z6huang@eng.ucsd.edu

Abstract
Through the tracking of biomarkers excreted from the epidermis, either by sweat or open wounds, the skin becomes a significant and noninvasive window into a person?s health. However, currently, there is a lack of standard methods that allow for both continuous monitoring of health and quick, automatic, and automated drug delivery via the skin. The overall goal of the proposed research is to build upon our strengths in designing wearable healthcare devices and point-of-care (POC) biosensor circuits and integrate diagnostics, data processing, and therapeutic functionalities onto the same stretchable platform for chronic wound management and post-surgery monitoring. The resulting system will be an entirely soft smart bandage that continuously monitors wound healing by analyzing the acquired biomarker concentration and temperature data locally, and triggers actuation, such as drug delivery. Near field communication (NFC) is employed to wirelessly transfer measured data to the patient or doctor for real-time wound status tracking. The technology developed here will have broad implications in smart wearable systems for medical applications and alter the treatment uptake and frequency based on the physiological reading such as metabolism of each individual patient.

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