9. tattoo-based wearable iontophoretic-biosensing device for noninvasive alcohol monitoring

Department: NanoEngineering
Research Institute Affiliation: Agile Center for Wearable Sensors (CWS)
Faculty Advisor(s): Joseph Wang | Patrick P. Mercier

Primary Student
Name: Jayoung Kim
Email: jak082@ucsd.edu
Phone: 858-822-1588
Grad Year: 2017

Student Collaborators
Itthipon Jeerapan, ijeerapa@ucsd.edu | Somayeh Imani, soimani@ucsd.edu

Abstract
We present a novel tattoo-based transdermal noninvasive alcohol monitoring device for wearable applications. The wearable alcohol sensor platform integrates an iontophoretic-biosensing system on a temporary tattoo platform along with flexible wireless electronics. The device delivers the pilocarpine drug via iontophoresis through the skin to induce sweat. Then, alcohol in the generated sweat is detected using an enzymatic reaction with alcohol-oxidase and a Prussian Blue transducer. The body-compliant flexible wireless electronics are coupled with a wearable tattoo sensor, which controls the iontophoretic/amperometric operations and enables wireless data transmission in real-time via Bluetooth communication. On-body evaluations with human subjects have been demonstrated using this completely wearable wireless tattoo sensor. Distinct differences in current responses are measured before and after alcohol consumption, reflecting the increased blood alcohol levels of the human subjects. This new wireless transdermal iontophoretic-bionsensing system holds considerable promise for noninvasive monitoring of alcohol consumption, and in practical applications can be readily extended to reduce alcohol-impaired driving accidents and alcohol abuse.

Industry Application Area(s)
Life Sciences/Medical Devices & Instruments | Materials

Related Links:

  1. http://pubs.acs.org/doi/abs/10.1021/acssensors.6b00356

Related Files:

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