193. new advances in acoustically propelled nanomotors.

Department: NanoEngineering
Faculty Advisor(s): Joseph Wang

Primary Student
Name: Fernando Soto
Email: f1soto@ucsd.edu
Phone: 858-822-1588
Grad Year: 2019

Student Collaborators
Fernando Soto, f1soto@eng.ucsd.edu

Abstract
Recent advances in the field of acoustically-powered nanomachines, triggered by ultrasound waves, have opened the door for new breakthrough biomedical applications.(1,2) These exerted sound waves used are relatively innocuous and easy to manipulate, offering unique advantages for enabling efficient and controllable motion in different biological media. This presentation will address a new a design of acoustic nanoswimmers, based on a nanoshell geometry(3), fabricated by a sphere template process. Furthermore, a detailed study of the parameters that affect the nanoshell propulsion (material density, size, and shape), indicates that the nanoshell motors exhibit a different propulsion behavior than that those predicted by recent theoretical and experimental models for acoustically-propelled nanomotors.(4,5) The practical application of the nanoshell was demonstrated by performing complex tasks, such as the capture and transport of multiple cargoes and the internalization and propulsion of the nanoshells inside live MCF-7 cancer cells. These new insights into acoustically propelled nanomotors could lead the way to design novel fuel-free nanoswimers capable of performing complex tasks for diverse biomedical applications. References 1. V. Garcia-Gradilla, J. Orozco, S. Sattayasamitsathit, F. Soto, F, Kuralay, A. Pourazary, A. Katzenberg, W. Gao, Y. Shen and J. Wang, ACS Nano, 2013, 7, 9232−9240. 2. W. Wang, S. Li, L. Mair, S. Ahmed, T. J. Huang and T. E. Mallouk, Angew. Chem., Int. Ed., 2014, 53, 3201-3204. 3. F. Soto, Gregory L. Wagner, V. Garcia-Gradilla, K.T. Gillespie, D. R. Lakshmipathy, E. Karshalev, C. Angell, Y. Chen and J. Wang, Nanoscale, 2016, DOI: 10.1039/C6NR06603H, 4. S. Ahmed, W. Wang, L. Bai, D. T. Gentekos, M. Hoyos and T.E. Mallouk, ACS Nano, 2016, 10, 4763-4769. 5. F. Nadal and E. Lauga, Phys. Fluids, 2014, 26, 082001.

Industry Application Area(s)
Life Sciences/Medical Devices & Instruments | Materials | Nanorobotics

Related Links:

  1. http://pubs.rsc.org/en/Content/ArticleLanding/2016/NR/C6NR06603H#!divAbstract
  2. https://youtu.be/fU2AvNBTpkM

Related Files:

  1. ultrasoundpowerednanomotor.jpg

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